* In studies conducted by Phenomix Sciences and Mayo Clinic, patients following a phenotype-guided weight-loss program have been shown to lose 2x more total body weight than those in a non-phenotype-guided program
Everyone’s body is different, specifically in how we process food, store and use energy and send signals to our brain.
The rate of food emptying from the gut varies, leaving some predisposed to feeling hungry faster than others after a meal.
The role of emotions and hunger signals varies, leaving some people thinking they need food when really their body has not yet received the “full” signal.
Some people burn through calories and store energy differently than others, which can lead to an energy (calorie storage) imbalance.
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Delay of feeling full during a meal, due to slow "hunger" signal to the brain.
Feeling hungry after eating, due to fast emptying of food from the stomach.
Eating in response to emotional triggers.
Satiation is the feeling of fullness and satisfaction that tells the brain when it’s time to stop eating. With a hungry brain, the brain is unable to determine when a meal is over, resulting in increased food consumption during a meal.
Satiation-related genes and/or low levels of certain metabolites predict the hungry brain obesity phenotype.
Your weight loss intervention will stimulate hormones that relay fullness, which is shown to decrease food intake and body weight among individuals with this dominant phenotype.
Satiety is the sense of feeling full during and after a meal. With a hungry gut, individuals often feel full during a meal, but themselves hungry shortly after eating. This is caused by the stomach moving the food out of the stomach faster than other phenotypes.
When you and your physician understand the root cause, "multi-omics", of your obesity then your physician will provide precision-based therapy targeting this specific phenotype.
Knowing when to eat, what to eat, and other complementary therapies to support weight loss makes for all the difference in the world.
Seeking food as a reaction to negative or positive emotions, or as a coping mechanism, can be defined as emotional hunger. Emotional hunger has been characterized by high levels of cravings, anxiety, and depression.
Presence of certain gene variants and/or high levels of certain metabolites may be used to predict the emotional hunger obesity phenotype.
Specific interventions such as cognitive therapy and medications that address some of the underlying emotions or psychological conditions may be helpful and lead to weight loss for patients with this dominant phenotype.
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